I won't even get into the world of autograph collecting. Don't have time today. BUT, I had an old TV circular autographed by Martin Milner and Kent McCord that I wanted to protect (ok, from the TV show Adam-12- look it up for those of you who don't appreciate good TV).
So I took it to the framing experts here in Durham- Lewis and Tiffany up at Bull City Art and Framing, downtown in Brightleaf Square. Technically speaking,- they know their shit. This is not your Michaels summer help run frame shop. This is where you take things you want done right. In fact, while I was in there Lewis was framing up a great piece of work which included Rocky Marciano's boxing glove, complete with pictures and everything.
As for my piece, he floated it inside the frame so that I could easily just remove it from the frame if I ever so desired, with no damage to the piece. I chose conservation glass, but they can use everything from regular old glass to museum quality preservation glass. And when I chose my frame, Tiffany took a picture of the piece and was able to show me the completed work right there on a big screen TV, so I'd know what it wold look like (other framers just show you a corner).
So there's my shameless pug (oops, meant plug, a shameless pug is a small dog that humps your leg). Maybe not so much a plug as a recommendation if you want a quality job done. Find their information in the links.